Ecosyste.ms: Issues
An open API service for providing issue and pull request metadata for open source projects.
GitHub / nlmixr2/nlmixr2est issues and pull requests
#372 - SAEM fit has very large parameter jump at first parameter to a "wrong" value and I don't understand why.
Issue -
State: open - Opened by iamstein over 1 year ago
- 7 comments
#370 - Only keep $parHistData and calc $parHist and $parHistStacked
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#369 - nlmixr2::nlmixr2 for SAEM - implement live traceplot (as done for Monolix)
Issue -
State: open - Opened by iamstein over 1 year ago
- 2 comments
#368 - Bring back `$parHistData`
Issue -
State: closed - Opened by mattfidler over 1 year ago
#367 - Fix 366
Pull Request -
State: closed - Opened by billdenney over 1 year ago
- 1 comment
#366 - `$parFixed` shows incorrect BSV
Issue -
State: closed - Opened by billdenney over 1 year ago
- 6 comments
#365 - Zero gradient reset issue
Issue -
State: open - Opened by mattfidler over 1 year ago
#364 - Return fit without table if table step fails
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#363 - return fit without table when table step fails
Issue -
State: closed - Opened by mattfidler over 1 year ago
#362 - Sticky theta reset
Issue -
State: open - Opened by mattfidler over 1 year ago
#361 - R crash with saem estimation and window size change
Issue -
State: closed - Opened by billdenney over 1 year ago
- 2 comments
#360 - Fix #359
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#359 - eta ~ 0 with correlated etas gives missing value error during printing
Issue -
State: closed - Opened by billdenney over 1 year ago
- 2 comments
#358 - However, as you pointed out, the bio-availability to the central compartment in `focei`'s linear compartment seems to not be working at all:
Issue -
State: open - Opened by mattfidler over 1 year ago
#357 - Add different method of fixing parameters in saem
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#356 - Provide different fixing mechanism for `saem`
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#355 - Remove `BSV(SD)` and `Shrink(SD)%` columns from `$parFixed` data.frame for models without etas
Issue -
State: open - Opened by billdenney over 1 year ago
#354 - Add mu2 processing
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#353 - Add scaling for `saem`
Issue -
State: open - Opened by mattfidler over 1 year ago
#352 - Aug pred fix
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#351 - Adds documentation for the nlmixr2 object
Pull Request -
State: closed - Opened by john-harrold over 1 year ago
#350 - The warning now is shown below
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#349 - Warn on time-varying covariate changes
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#348 - Problem with SAEM covariate modeling
Issue -
State: closed - Opened by roninsightrx over 1 year ago
- 24 comments
#347 - Add Regression optimization for time-varying covariates instead of simply mcmc?
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#346 - Simplify numbers in `$parFixed`
Issue -
State: open - Opened by billdenney over 1 year ago
- 3 comments
#345 - Update documentation to link parts together (and some minor code formatting changes)
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#344 - Suggestion: Deprecate `nlmixr2NlmeControl()`
Issue -
State: closed - Opened by billdenney over 1 year ago
- 2 comments
#343 - saem estimation not occurring in parallel
Issue -
State: closed - Opened by billdenney over 1 year ago
- 9 comments
#342 - vpcSim works with etas set to 0
Pull Request -
State: closed - Opened by billdenney over 1 year ago
- 6 comments
#341 - `vpcSim()` requires that etas set to zero must be in the dataset
Issue -
State: closed - Opened by billdenney over 1 year ago
- 3 comments
#340 - Make addCwres() error clearer for model with no etas
Pull Request -
State: closed - Opened by billdenney over 1 year ago
- 1 comment
#339 - Make error clearer for `addCwres()` when the model has no random effects
Issue -
State: closed - Opened by billdenney over 1 year ago
#338 - Add mu ref fix
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#337 - Improved digest method
Issue -
State: closed - Opened by billdenney over 1 year ago
- 7 comments
#336 - 335 for $datamerge family prefer fit object instead of original data
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#335 - For `$dataMerge` family prefer fit object instead of original data
Issue -
State: closed - Opened by mattfidler over 1 year ago
#333 - Add simulation method
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#332 - Add simulation method, ie `est="simulation"`, "
Issue -
State: closed - Opened by snailittle over 1 year ago
- 4 comments
#331 - Documentation Request: How can I use alternate distributions?
Issue -
State: closed - Opened by billdenney over 1 year ago
- 2 comments
#330 - ID isn't really needed when there is no etas for models.
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#329 - Rebuild documentation
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#328 - Feature Request Discussion: Extend what can be mu-referenced by dataset and model modification
Issue -
State: closed - Opened by billdenney over 1 year ago
- 6 comments
#327 - eta on residuals for focei should reset to zero every iteration
Issue -
State: open - Opened by mattfidler over 1 year ago
#326 - Allow for babelmixr2::pkncaControl() not to set genRxControl
Pull Request -
State: closed - Opened by billdenney over 1 year ago
- 1 comment
#325 - Make package installation consistent; fix typos; use label()
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#324 - Speed up some testing by minimizing the fit iterations
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#323 - 311 condition numbers
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#322 - 316 wrong initial values in nlmixr2 object
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#321 - 318 fix bound
Pull Request -
State: closed - Opened by billdenney over 1 year ago
#320 - Only use absolute value of the difference
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
- 8 comments
#319 - drop stan headers and eigen
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#318 - Boundary issue triggered when lower and upper bounds are on both sides of zero
Issue -
State: closed - Opened by billdenney over 1 year ago
- 1 comment
#317 - Drop StanHeaders/RcppEigen
Issue -
State: closed - Opened by mattfidler over 1 year ago
#316 - Wrong initial values in nlmixr2 object
Issue -
State: closed - Opened by PhilP86 over 1 year ago
- 2 comments
#315 - Make `nlmixr2` default to have the nonmem input data to do modeling on...
Issue -
State: closed - Opened by mattfidler over 1 year ago
#314 - Be a bit more robust with `saem` inverses?
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#313 - Update compilation/linker flags for StanHeaders 2.26 compatibility
Pull Request -
State: closed - Opened by andrjohns over 1 year ago
- 5 comments
#312 - Allow lower diagonal zeros to be fixed in a full covariance matrix
Issue -
State: open - Opened by mattfidler over 1 year ago
#311 - Condition Numbers
Issue -
State: closed - Opened by mattfidler over 1 year ago
#310 - Fallback to old method
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#309 - Fix failing `nlmixr2est`
Issue -
State: closed - Opened by mattfidler over 1 year ago
#308 - Make some focei methods for simulation that are closer to est model
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
- 1 comment
#307 - `vpcSim()` converts `keep` columns to numeric
Issue -
State: closed - Opened by billdenney over 1 year ago
- 1 comment
Labels: duplicate
#306 - `simVpc` needs to more closely match the estimated model
Issue -
State: closed - Opened by mattfidler over 1 year ago
- 2 comments
#305 - Get the confidence intervals from the defined uncertainty method
Issue -
State: closed - Opened by billdenney over 1 year ago
- 2 comments
#304 - 302 mu reference definition isnt correct for non mu referenced model
Pull Request -
State: closed - Opened by mattfidler over 1 year ago
#303 - Feature Brainstorm: Documentation of Covariates?
Issue -
State: open - Opened by billdenney over 1 year ago
- 2 comments
#302 - Mu reference definition isn't correct for non-mu referenced model
Issue -
State: closed - Opened by mattfidler almost 2 years ago
- 1 comment
#301 - Inaccurate reporting of only NA values for a subject
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 4 comments
#299 - Remove debugging statement
Pull Request -
State: closed - Opened by billdenney almost 2 years ago
#298 - Should "here!!!" print during the covariance step?
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 1 comment
#297 - `tableControl(keep = )` is ignored with `est = "rxSolve"`; AMT cannot be kept with SAEM or FOCEI
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 6 comments
#296 - Feature Request: Mu referenced focei can use linear models to speed up and stablize estimation
Issue -
State: open - Opened by mattfidler almost 2 years ago
#295 - How to track down "NAs introduced by coercion"
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 4 comments
#294 - Feature Request: Allow Hessian for inner problem to be inferred from the likelihood hessian estimate
Issue -
State: open - Opened by mattfidler almost 2 years ago
- 2 comments
#293 - Speed up testing
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 3 comments
#292 - Fix rxode2 #364
Pull Request -
State: closed - Opened by billdenney almost 2 years ago
- 8 comments
#291 - For discussion (maybe a feature request, maybe not): `vcov()` gives a different set of estimated parameters than `fixef()`
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 2 comments
#290 - 289 issue in obtaining model estimates
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#289 - Issue in obtaining model estimates
Issue -
State: closed - Opened by diabloyg almost 2 years ago
- 4 comments
#288 - Test nonmu and add test case for merge (and unsuccesful merge)
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#287 - Another merge issue
Issue -
State: closed - Opened by mattfidler almost 2 years ago
#286 - Test estimation of combined `linCmt()`, ODE models
Issue -
State: open - Opened by billdenney almost 2 years ago
- 8 comments
#285 - 284 include log likelihood per observation when adding cwres
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#284 - Include log-likelihood per observation when adding `cwres`
Issue -
State: closed - Opened by mattfidler almost 2 years ago
#283 - 282 $etah not available for saem needs cwres but doesnt pull over standard errors
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#282 - `$etaH` not available for `saem`. Needs `cwres` but doesn't pull over standard errors.
Issue -
State: closed - Opened by mattfidler almost 2 years ago
#281 - Fuzzy bad, silver good
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#280 - Piping bioavailability with an nlmixr2fit object fails while rxUi objects work
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 1 comment
#279 - Update ci
Pull Request -
State: closed - Opened by billdenney almost 2 years ago
#278 - Start testing bill's example
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#277 - Add ARMA_64BIT_WORD
Pull Request -
State: closed - Opened by mattfidler almost 2 years ago
#276 - `ARMA_64BIT_WORD`
Issue -
State: closed - Opened by mattfidler almost 2 years ago
#275 - Update CI workflow to current versions
Pull Request -
State: closed - Opened by billdenney almost 2 years ago
- 5 comments
#274 - In focei, text covariates are converted to doubles (but it appears that the model still estimates)
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 2 comments
#273 - Re-allow ID to be something other than numeric for focei
Pull Request -
State: closed - Opened by billdenney almost 2 years ago
- 3 comments
#272 - Error of "no rows in event table or input data" in model that previously worked
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 3 comments
#271 - Does `DV` have to be numeric?
Issue -
State: open - Opened by billdenney almost 2 years ago
- 2 comments
#270 - Fuzzy text in print header for FOCEi
Issue -
State: closed - Opened by billdenney almost 2 years ago
- 5 comments